UDK 615.074
Kovalenko Svetlana Nykolaevna, Shkliaiev Sergey Anatolevych,
Baranova Inna Ivanovna
VALIDATION OF HPLC METHOD FOR DETERMINING THIOCTIC ACID IN THE COMPOUND DRUG FOR EXTERNAL USE TO TREAT DIABETIC ULCERS
National University of Pharmacy, Kharkov, Str. Pushkinskay, 53, 06002
The pharmacopoeia definition procedure of thioctic acid by a high performance liquid chromatography in the new complex medicine was adopted and validated. It was shown that the validation criterion of the procedure is conformed to the requirements of the State pharmacopoeia of Ukraine for assay with limits of active ingredients ± 5 %. There is no influence of matrix components on validation criteria.